The presentation focuses on cyanobacterial metabolites relevant to water quality, including cyanotoxins, cyanopeptides, and volatiles. It begins with an introduction to cyanobacteria and their toxins (cyanotoxins), followed by a discussion on the effects of climate change and the emergence of microcystins. The presentation highlights cyanobacterial metabolites using CyanoMetDB, explores new microginins from Greek freshwater sources, and compares targeted vs. untargeted screening of cyanometabolites. Additionally, it covers the cyanobacteria volatilome, their T&O compounds, tools for non-targeted analysis, and the presence of T&O and VOCs in Spirulina products.